Engineering Mechanics

Proceedings Vol. 24 (2018)

ENGINEERING MECHANICS 2018

Copyright © 2018 Institute of Theoretical and Applied Mechanics of the Cech Academy of Sciences, Prague

 

Macháček O., et al.
pages 521 - 524, full text

Micro-fluidic systems are used in approximately 30 years for detect or separate biological molecules which are contain in a biological medium (blood, serum, etc.). The technique of separation is based on magnetic force acting on the magnetic particles which are added to the medium. One way to increase separation efficiency is to optimize the magnetic circuit. Two versions of magnetic circuit for the micro-fluidic system are designed, tested and compared in this study. The first of them has solid pole pieces (without grooves), the second one is provided with grooves which are oriented perpendicular to the direction of a fluid flow through the system. A suitable geometry of the grooves was chosen using a FEM model which is verified by measurement. Hypothesis that the grooved pole pieces ensure higher amount of captured particles in the system in comparison with the case of solid pole pieces was confirmed. But, the comparison of the captured particles amount was made just visually. Therefore, the amount of particles which are washout during a flow test should be evaluated by more quantifiable method in future study, for example using Beer-Lambert law.

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